Predicting treatment response before treatment begins

Episteme Prognostics’ mission is to fundamentally transform how cancer is treated. We are developing precision diagnostics designed to help identify which patients are most likely to benefit from cancer therapies. Our goal is to ensure that chemotherapy is given only to patients who are likely to benefit, while guiding others toward the best alternative treatment options.

The Problem:

Chemotherapy remains a cornerstone of cancer treatment. But not every patient responds.

  • Each year, 10-13 million cancer patients receive chemotherapy.
  • 7-9 million patients do not respond.

Treatment failure can lead to poorer outcomes, fewer options, and an immense emotional and financial burden.

Our First Application is PancEpistemeDx™

Our first planned diagnostic to predict chemotherapy response in pancreatic cancer using tumor chromatin accessibility signatures.

  • Predict Response

Identify patients unlikely to respond to chemotherapy.

  • Inform Treatment

Provide actionable information before treatment decisions are made.

  • Advance Precision Oncology

Extend our approach to additional therapies and cancer types.

Beyond Pancreatic Cancer

One platform. Multiple applications.

  • Cancer Therapy Selection

Improve outcomes by matching patients to the right therapy.

  • Biopharma Drug Development

Accelerate clinical development and identify responsive populations.

  • Companion Diagnostics

Develop diagnostic solutions for targeted and epigenetic therapies.